Publications 2016


ARIA 2016: Care pathways implementing emerging technologies for predictive medicine in rhinitis and asthma across the life cycle.
Bousquet J, Hellings PW, Agache I, Bedbrook A, Bachert C, Bergmann KC, Bewick M, Bindslev-Jensen C, Bosnic-Anticevitch S, Bucca C, Caimmi DP, Camargos PA, Canonica GW, Casale T, Chavannes NH, Cruz AA, De Carlo G, Dahl R, Demoly P, Devillier P, Fonseca J, Fokkens WJ, Guldemond NA, Haahtela T, Illario M, Just J, Keil T, Klimek L, Kuna P, et al.
Clin Transl Allergy. 2016 Dec 30;6:47.

T cells promote bronchial epithelial cells secretion of Matrix-Metalloproteinase-9 via a C-C chemokine receptor type 2 pathway, implications for chronic lung allograft dysfunction.
Pain M, Royer PJ, Loy J, Girardeau A1, Tissot A1, Lacoste P, Roux A, Reynaud-Gaubert M, Kessler R, Mussot S, Dromer C, Brugière O, Mornex JF, Guillemain R, Dahan M, Knoop C, Botturi K, Pison C, Danger R, Brouard S, Magnan A; COLT consortium.
Am J Transplant. 2016 Dec 16. doi: 10.1111/ajt.14166. [Epub ahead of print]

Seipin regulates ER-lipid droplet contacts and cargo delivery.
Salo VT, Belevich I, Li S, Karhinen L, Vihinen H, Vigouroux C, Magré J, Thiele C, Hölttä-Vuori M, Jokitalo E, Ikonen E.
EMBO J. 2016 Dec 15;35(24):2699-2716.

Soluble Milk Protein Supplementation with Moderate Physical Activity Improves Locomotion Function in Aging Rats.
Lafoux A, Baudry C, Bonhomme C, Le Ruyet P, Huchet C.
PLoS One. 2016 Dec 14;11(12):e0167707.

Spermaurin, an La1-like peptide from the venom of the scorpion Scorpio maurus palmatus, improves sperm motility and fertilization in different mammalian species.
Martinez G, Hograindleur JP, Voisin S, Abi Nahed R, Abd E Aziz TM, Escoffier J, Bessonnat J, Fovet CM, De Waard M, Hennebicq S, Aucagne V, Ray PF, Schmitt E, Bulet P, Arnoult C.
Mol Hum Reprod. 2016 Dec 8. doi: 10.1093/molehr/gaw075. [Epub ahead of print]

Cardiac Phenotype and Long-Term Follow-Up of Patients With Mutations in NKX2-5 Gene.
Maury P, Gandjbakhch E, Baruteau AE, Bessière F, Kyndt F, Bouvagnet P, Rollin A, Bonnet D, Probst V, Maltret A.
J Am Coll Cardiol. 2016 Nov 29;68(21):2389-2390. doi: 10.1016/j.jacc.2016.08.064.

PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study.
Schmidt AF, Swerdlow DI, Holmes MV, Patel RS, Fairhurst-Hunter Z, Lyall DM, Hartwig FP, Horta BL, Hyppönen E, Power C, Moldovan M, van Iperen E, Hovingh GK, Demuth I, Norman K, Steinhagen-Thiessen E, Demuth J, Bertram L, Liu T, Coassin S, Willeit J, Kiechl S, Willeit K, Mason D, Wright J, Morris R, Wanamethee G, Whincup P, Ben-Shlomo Y, et al.
Lancet Diabetes Endocrinol. 2016 Nov 28. pii: S2213-8587(16)30396-5. doi: 10.1016/S2213-8587(16)30396-5. [Epub ahead of print]

Incomplete Timothy syndrome secondary to a mosaic mutation of the CACNA1C gene diagnosed using next-generation sequencing.
Baurand A, Falcon-Eicher S, Laurent G, Villain E, Bonnet C, Thauvin-Robinet C, Jacquot C, Eicher JC, Gourraud JB, Schmitt S, Bézieau S, Giraud M, Dumont S, Kuentz P, Probst V, Burguet A, Kyndt F, Faivre L.
Am J Med Genet A. 2016 Nov 21. doi: 10.1002/ajmg.a.38045. [Epub ahead of print]

Chemokine receptors in allergic diseases.
Castan L, Magnan A, Bouchaud G.
Allergy. 2016 Nov 16. doi: 10.1111/all.13089. [Epub ahead of print]

Glycemic control impacts the relationship between plasma PCSK9 and LDL cholesterol in type 1 diabetes.
Laugier-Robiolle S, Vergès B, Le Bras M, Gand E, Bouillet B, Saulnier PJ, Le May C, Pichelin M, Maréchaud R, Petit JM, Hadjadj S, Cariou B.
Diabetes Obes Metab. 2016 Nov 2. doi: 10.1111/dom.12819. [Epub ahead of print]

Non-vitamin K antagonist oral anticoagulants and heart failure.
Isnard R, Bauer F, Cohen-Solal A, Damy T, Donal E, Galinier M, Hagège A, Jourdain P, Leclercq C, Sabatier R, Trochu JN, Cohen A.
Arch Cardiovasc Dis. 2016 Nov;109(11):641-650. doi: 10.1016/j.acvd.2016.08.001. Review.
Mechanotransduction via the nuclear envelope: a distant reflection of the cell surface.
Aureille J, Belaadi N, Guilluy C.
Curr Opin Cell Biol. 2016 Oct 26. pii: S0955-0674(16)30171-5. doi: 10.1016/j.ceb.2016.10.003. [Epub ahead of print]

Seipin deficiency alters brown adipose tissue thermogenesis and insulin sensitivity in a non-cell autonomous mode.
Dollet L, Magré J, Joubert M, Le May C, Ayer A, Arnaud L, Pecqueur C, Blouin V, Cariou B, Prieur X.
Sci Rep. 2016 Oct 17;6:35487.

Anticonvulsant activity of an active fraction extracted from Crinum jagus L. (Amaryllidaceae), and its possible effects on fully kindled seizures, depression-like behaviour and oxidative stress in experimental rodent models.
Taiwe GS, Tchoya TB, Menanga JR, Dabole B, De Waard M.
J Ethnopharmacol. 2016 Oct 7. pii: S0378-8741(16)31205-3. doi: 10.1016/j.jep.2016.10.023. [Epub ahead of print]

One-year metreleptin therapy decreases PCSK9 serum levels in diabetic patients with monogenic lipodystrophy syndromes.
Vatier C, Arnaud L, Prieur X, Guyomarch B, Le May C, Bigot E, Pichelin M, Daguenel A, Vantyghem MC, Gautier JF, Vigouroux C, Cariou B.
Diabetes Metab. 2016 Sep 27. pii: S1262-3636(16)30479-7. doi: 10.1016/j.diabet.2016.08.004. [Epub ahead of print]

Consensus statement on the management of dyslipidaemias in adults.
French Society of Endocrinology (SFE); Francophone Society of Diabetes (SFD); New French Society of Atherosclerosis (NSFA), Béliard S, Bonnet F, Bouhanick B, Bruckert E, Cariou B, Charrière S, Durlach V, Moulin P, Valéro R, Vergès B.
Diabetes Metab. 2016 Sep 19. pii: S1262-3636(16)30472-4. doi: 10.1016/j.diabet.2016.07.033. [Epub ahead of print]

Variants in the SCN5A Promoter Associated With Various Arrhythmia Phenotypes.
Yagihara N, Watanabe H, Barnett P, Duboscq-Bidot L, Thomas AC, Yang P, Ohno S, Hasegawa K, Kuwano R, Chatel S, Redon R, Schott JJ, Probst V, Koopmann TT, Bezzina CR, Wilde AA, Nakano Y, Aiba T, Miyamoto Y, Kamakura S, Darbar D, Donahue BS, Shigemizu D, Tanaka T, Tsunoda T, Suda M, Sato A, Minamino T, Endo N, Shimizu W, Horie M, Roden DM, Makita N.
J Am Heart Assoc. 2016 Sep 13;5(9).

Effects of long-term active immunization with the second extracellular loop of human  Bêta1- or Bêta3-adrenoceptors in thoracic aorta and mesenteric arteries in Lewis rats.
Montaudon E, Dubreil L, Lalanne V, Jagu B, Toumaniantz G, Thorin C, Henrion D, Desfontis JC, Martignat L, Mallem MY.
Vascul Pharmacol. 2016 Sep 9. pii: S1537-1891(16)30159-8. doi: 10.1016/j.vph.2016.09.004. [Epub ahead of print]

Biallelic PPA2 Mutations Cause Sudden Unexpected Cardiac Arrest in Infancy.
Guimier A, Gordon CT, Godard F, Ravenscroft G, Oufadem M, Vasnier C, Rambaud C, Nitschke P, Bole-Feysot C, Masson C, Dauger S, Longman C, Laing NG, Kugener B, Bonnet D, Bouvagnet P, Di Filippo S, Probst V, Redon R, Charron P, Rötig A, Lyonnet S, Dautant A, de Pontual L, di Rago JP, Delahodde A, Amiel J.
Am J Hum Genet. 2016 Sep 1;99(3):666-73.

Biallelic Variants in UBA5 Reveal that Disruption of the UFM1 Cascade Can Result in Early-Onset Encephalopathy.
Colin E, Daniel J, Ziegler A, Wakim J, Scrivo A, Haack TB, Khiati S, Denommé AS, Amati-Bonneau P, Charif M, Procaccio V, Reynier P, Aleck KA, Botto LD, Herper CL, Kaiser CS, Nabbout R, N'Guyen S, Mora-Lorca JA, Assmann B, Christ S, Meitinger T, Strom TM, Prokisch H; FREX Consortium, Miranda-Vizuete A, Hoffmann GF, Lenaers G, Bomont P, Liebau E, Bonneau D.
Am J Hum Genet. 2016 Sep 1;99(3):695-703.

HIV-Tat induces a decrease in IKr and IKsvia reduction in phosphatidylinositol-(4,5)-bisphosphate availability.
Es-Salah-Lamoureux Z, Jouni M, Malak OA, Belbachir N, Al Sayed ZR, Gandon-Renard M, Lamirault G, Gauthier C, Baró I, Charpentier F, Zibara K, Lemarchand P, Beaumelle B, Gaborit N, Loussouarn G.
J Mol Cell Cardiol. 2016 Aug 31;99:1-13. doi: 10.1016/j.yjmcc.2016.08.022. [Epub ahead of print]

Polymorphism in programmed cell death 1 gene is strongly associated with lung and kidney allograft survival in recipients from CMV-positive donors.
Forconi C, Gatault P, Miquelestorena-Standley E, Noble J, Al-Hajj S, Guillemain R, Stern M, Hoffmann T, Prat L, Suberbielle C, Masson E, Cesbron-Gautier A, Gaudy-Graffin C, Goudeau A, Thibault G, Ivanes F, Guibon R, Kazma I, Lebranchu Y, Büchler M, Magnan A, Halimi JM, Baron C.

J Heart Lung Transplant. 2016 Aug 26. pii: S1053-2498(16)30295-9. doi: 10.1016/j.healun.2016.08.014. [Epub ahead of print]

FGF21 Improves the Adipocyte Dysfunction Related to Seipin-Deficiency.
Dollet L, Levrel C, Coskun T, Le Lay S, Le May C, Ayer A, Venara Q, Adams AC, Gimeno RE, Magré J, Cariou B, Prieur X.
Diabetes. 2016 Aug 23. pii: db160327. [Epub ahead of print]

PCSK9 and atherosclerosis: Beyond LDL-cholesterol lowering.
Cariou B, Ding Z, Mehta JL.
Atherosclerosis. 2016 Aug 20. pii: S0021-9150(16)31256-4. doi: 10.1016/j.atherosclerosis.2016.08.007. [Epub ahead of print]

Anticonvulsant effects of iridoid glycosides fraction purified from Feretia apodanthera Del. (Rubiaceae) in experimental mice models of generalized tonic-clonic seizures.
Taiwe GS, Dabole B, Tchoya TB, Menanga JR, Dzeufiet PD, De Waard M.
BMC Complement Altern Med. 2016 Aug 12;16(1):285.

Ivabradine and metoprolol differentially affect cardiac glucose metabolism despite similar heart rate reduction in a mouse model of dyslipidemia.
Vaillant F, Lauzier B, Ruiz M, Shi Y, Lachance D, Rivard ME, Bolduc V, Thorin E, Tardif JC, Des Rosiers C.
Am J Physiol Heart Circ Physiol. 2016 Aug 5:ajpheart.00789.2015.

hiPSC-derived cardiomyocytes from Brugada Syndrome patients without identified mutations do not exhibit clear cellular electrophysiological abnormalities.
Veerman CC, Mengarelli I, Guan K, Stauske M, Barc J, Tan HL, Wilde AA, Verkerk AO, Bezzina CR.
Sci Rep. 2016 Aug 3;6:30967.

Sustained quality of life improvement after intracoronary injection of autologous bone marrow cells in the setting of acute myocardial infarction: results from the BONAMI trial.
Lamirault G, de Bock E, Sébille S, Delasalle B, Roncalli J, Susen S, Piot C, Trochu JN, Teiger E, Neuder Y, Le Tourneau T, Manrique A, Hardouin J-B, Lemarchand P.
Quality of Life Research 2016, Jul 20. [Epub ahead of print].
Proteomic analysis of native cerebellar iFGF14 complexes.
Bosch MK, Nerbonne JM, Townsend RR, Miyazaki H, Nukina N, Ornitz DM, Marionneau C.
Channels (Austin). 2016 Jul 3;10(4):297-312.

Protein partners of the calcium channel ß subunit highlight new cellular functions.
Rima M, Daghsni M, Fajloun Z, M'rad R, Brusés JL, Ronjat M, De Waard M.
Biochem J. 2016 Jul 1;473(13):1831-44.

Is there an inherited anatomical conformation favoring aneurysmal formation of the anterior communicating artery?
Bourcier R, Lenoble C, Guyomarch-Delasalle B, Daumas-Duport B, Papagiannaki C, Redon R, Desal H.
J Neurosurg. 2016 Jun 17:1-8. [Epub ahead of print]

Under Pressure: Mechanical Stress Management in the Nucleus.
Belaadi N, Aureille J, Guilluy C.
Cells. 2016 Jun 14;5(2). pii: E27. doi: 10.3390/cells5020027.

Dysfunction of the Voltage-Gated K+ Channel 2 Subunit in a Familial Case of Brugada Syndrome.
Portero V, Le Scouarnec S, Es-Salah-Lamoureux Z, Burel S, Gourraud JB, Bonnaud S, Lindenbaum P, Simonet F, Violleau J, Baron E, Moreau E, Scott C, Chatel S, Loussouarn G, O'Hara T, Mabo P, Dina C, Le Marec H, Schott JJ, Probst V, Baró I, Marionneau C, Charpentier F, Redon R.
J Am Heart Assoc. 2016 Jun 10;5(6). pii: e003122. doi: 10.1161/JAHA. 115.003122.

Chronic Lung Allograft Dysfunction: A Systems Review of Mechanisms.
Royer PJ, Olivera-Botello G, Koutsokera A, Aubert JD, Bernasconi E, Tissot A, Pison C, Nicod L, Boissel JP, Magnan A; SysCLAD consortium.
Transplantation. 2016 Jun 2. [Epub ahead of print]

SORL1 rare variants: a major risk factor for familial early-onset Alzheimer's disease.
Nicolas G, Charbonnier C, Wallon D, Quenez O, Bellenguez C, Grenier-Boley B, Rousseau S, Richard AC, Rovelet-Lecrux A, Le Guennec K, Bacq D, Garnier JG, Olaso R, Boland A, Meyer V, Deleuze JF, Amouyel P, Munter HM, Bourque G, Lathrop M, Frebourg T, Redon R, Letenneur L, Dartigues JF, Génin E, Lambert JC, Hannequin D, Campion D; CNR-MAJ collaborators.
Mol Psychiatry. 2016 Jun;21(6):831-6.

Variants of Transient Receptor Potential Melastatin Member 4 in Childhood Atrioventricular Block.
Syam N, Chatel S, Ozhathil LC, Sottas V, Rougier JS, Baruteau A, Baron E, Amarouch MY, Daumy X, Probst V, Schott JJ, Abriel H.
J Am Heart Assoc. 2016 May 20;5(5).

Maladaptative autophagy impairs adipose function in Congenital Generalized Lipodystrophy due to cavin-1 deficiency.
Salle-Teyssières L, Auclair M, Terro F, Nemani M, Elsayed SM, Elsobky E, Lathrop M, Délépine M, Lascols O, Capeau J, Magré J, Vigouroux C.
J Clin Endocrinol Metab. 2016 May 4:jc20161086. [Epub ahead of print]

Utilizing the Jaccard index to reveal population stratification in sequencing data: a simulation study and an application to the 1000 Genomes Project.
Prokopenko D1, Hecker J1, Silverman EK2, Pagano M3, Nöthen MM4, Dina C5, Lange C6, Fier HL7.
Bioinformatics. 2016 May 1;32(9):1366-72.

The Brugada Syndrome: A Rare Arrhythmia Disorder with Complex Inheritance.
Gourraud JB, Barc J, Thollet A, Le Scouarnec S, Le Marec H, Schott JJ, Redon R, Probst V.
Front Cardiovasc Med. 2016 Apr 25;3:9.

Intramyocardial transplantation of mesenchymal stromal cells for chronic myocardial ischemia and impaired left ventricular function: Results of the MESAMI 1 pilot trial.
Guijarro D, Lebrin M, Lairez O, Bourin P, Piriou N, Pozzo J, Lande G, Berry M, Le Tourneau T, Cussac D, Sensebe L, Gross F, Lamirault G, Huynh A, Manrique A, Ruidavet JB, Elbaz M, Trochu JN, Parini A, Kramer S, Galinier M, Lemarchand P, Roncalli J.
Int J Cardiol. 2016 Apr 15;209:258-65.
Loss of Iroquois homeobox transcription factors 3 and 5 in osteoblasts disrupts cranial mineralization.
Cain CJ, Gaborit N, Lwin W, Barruet E, Ho S, Bonnard C, Hamamy H, Shboul M, Reversade B, Kayserili H, Bruneau BG, Hsiao EC.
Bone Rep. 2016 Apr 13;5:86-95.

Identification of novel APOB mutations by targeted next-generation sequencing for the molecular diagnosis of familial hypobetalipoproteinemia.
Rimbert A, Pichelin M, Lecointe S, Marrec M, Le Scouarnec S, Barrak E, Croyal M, Krempf M, Le Marec H, Redon R, Schott JJ, Magré J,        Cariou B.
Atherosclerosis. 2016 Apr 11;250:52-56.

Focal adhesions, stress fibers and mechanical tension.
Burridge K, Guilluy C.
Exp Cell Res. 2016 Apr 10;343(1):14-20.

Impact of pre-transplant diffusion lung capacity for nitric oxide (DLNO) and of DLNO/pre-transplant diffusion lung capacity for carbon monoxide (DLNO/DLCO) ratio on pulmonary outcomes in adults receiving allogeneic stem cell transplantation for hematological diseases.
Le Bourgeois A, Malard F, Chevallier P, Urbistandoy G, Guillaume T, Delaunay J, Peterlin P, Lemarchand P, Germaud P, Mohty M, Moreau P, Chambellan A.
Bone Marrow Transplant. 2016 Apr;51(4):589-92.

ABCA7 rare variants and Alzheimer disease risk.
Le Guennec K, Nicolas G, Quenez O, Charbonnier C, Wallon D, Bellenguez C, Grenier-Boley B, Rousseau S, Richard AC, Rovelet-Lecrux A, Bacq D, Garnier JG, Olaso R, Boland A, Meyer V, Deleuze JF, Amouyel P, Munter HM, Bourque G, Lathrop M, Frebourg T, Redon R, Letenneur L, Dartigues JF, Pasquier F, Rollin-Sillaire A, Génin E, Lambert JC, Hannequin D, Campion D; CNR-MAJ collaborators.
Neurology. 2016 Apr 1. pii: 10.1212/WNL.0000000000002627. [Epub ahead of print].

Predictors of ventricular remodelling in patients with reperfused acute myocardial infarction and left ventricular dysfunction candidates for bone marrow cell therapy: insights from the BONAMI trial.
Manrique A, Lemarchand P, Delasalle B, Lairez O, Sportouch-Duckan C, Lamirault G, Le Corvoisier P, Neuder Y, Richardson M, Lebon A, Roncalli J, Piot C, Trochu JN, Teiger E, Hossein-Foucher C, Le Tourneau T.
Eur J Nucl Med Mol Imaging. 2016 Apr;43(4):740-8.

De Novo Truncating Mutations in the kinetochore-microtubules attachment gene CHAMP1 Cause Syndromic Intellectual Disability.
Isidor B, Küry S, Rosenfeld JA, Besnard T, Schmitt S, Joss S, Davies SJ, Lebel RR, Henderson A, Schaaf CP, Streff HE, Yang Y, Jain V, Chida N, Latypova X, Caignec CL, Cogné B, Mercier S, Vincent M, Colin E, Bonneau D, Denommé AS, Parent P, Gilbert-Dussardier B, Odent S, Toutain A, Piton A, Dina C, Donnart A, Lindenbaum P, Charpentier E, Redon R, Iemura K, Ikeda M, Tanaka K, Bézieau S.
Hum Mutat. 2016 Apr;37(4):354-8.

Indicators of iron status are correlated with adiponectin expression in adipose tissue of patients with morbid obesity.
Pihan-Le Bars F, Bonnet F, Loréal O, Le Loupp AG, Ropert M, Letessier E, Prieur X, Bach K, Deugnier Y, Fromenty B, Cariou B.
Diabetes Metab. 2016 Apr;42(2):105-11.

Prognostic significance of fever-induced Brugada syndrome.
Mizusawa Y, Morita H, Adler A, Havakuk O, Thollet A, Maury P, Wang DW, Hong K, Gandjbakhch E, Sacher F, Hu D, Amin AS, Lahrouchi N, Tan HL, Antzelevitch C, Probst V, Viskin S, Wilde AA.
Heart Rhythm. 2016 Mar 23. pii: S1547-5271(16)30088-1.

Design of ionizable lipids to overcome the limiting step of endosomal escape - Application in the intracellular delivery of mRNA, DNA and siRNA.
Habrant D, Peuziat P, Colombani T, Dallet L, Gehin J, Goudeau E, Evrard B, Lambert O, Haudebourg T, Pitard B.
J Med Chem. 2016 Mar 4. [Epub ahead of print]

Important role of phosphoramido linkage in imidazole-based dioleyl helper lipids for liposome stability and primary cell transfection.
Mével M, Haudebourg T, Colombani T, Peuziat P, Dallet L, Chatin B, Lambert O, Berchel M, Montier T, Jaffrès PA, Lehn P, Pitard B.
J Gene Med. 2016 Jan-Mar;18(1-3):3-15.

Mesenchymal stem cells induce suppressive macrophages through phagocytosis in a mouse model of asthma.
Braza F*, Dirou S*, Forest V*, Sauzeau V, Hassoun D, Chesné J, Cheminant-Muller MA, Sagan C, Magnan A, Lemarchand P.
Stem Cells. 2016 Feb 17. doi: 10.1002/stem.2344. [Epub ahead of print]
G protein-gated IKACh channels as therapeutic targets for treatment of sick sinus syndrome and heart block.
Mesirca P, Bidaud I, Briec F, Evain S, Torrente AG, Le Quang K, Leoni AL, Baudot M, Marger L, Chung You Chong A, Nargeot J, Striessnig J, Wickman K, Charpentier F, Mangoni ME.

Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):E932-41. doi: 10.1073/pnas.1517181113. Epub 2016 Feb 1.

Cardiac Protective Effects of Moringa oleifera Seeds in Spontaneous Hypertensive Rats.
Randriamboavonjy JI, Loirand G, Vaillant N, Lauzier B, Derbré S, Michalet S, Pacaud P, Tesse A.
Am J Hypertens. 2016 Feb 10. pii: hpw001. [Epub ahead of print]

Using magnets and magnetic beads to dissect signaling pathways activated by mechanical tension applied to cells.
Marjoram RJ, Guilluy C, Burridge K.
Methods. 2016 Feb 1;94:19-26. doi: 10.1016/j.ymeth.2015.09.025. Epub 2015 Sep 30.

Search for Rare Copy-Number Variants in Congenital Heart Defects Identifies Novel Candidate Genes and a Potential Role for FOXC1 in Patients With Coarctation of the Aorta.
Sanchez-Castro M, Eldjouzi H, Charpentier E, Busson PF, Hauet Q, Lindenbaum P, Delasalle-Guyomarch B, Baudry A, Pichon O, Pascal C, Lefort B, Bajolle F, Pezard P, Schott JJ, Dina C, Redon R, Gournay V, Bonnet D, Le Caignec C.
Circ Cardiovasc Genet. 2016 Feb;9(1):86-94.

[Importance of comorbidities in the anemia of COPD: Economic implications and 3-year survival analysis].
Menou A, Pain M, Pivette J, Chenivesse C, Magnan A, Chambellan A.
Rev Mal Respir. 2016 Jan 20. pii: S0761-8425(15)01204-8. doi: 10.1016/j.rmr.2015.12.008. [Epub ahead of print]

Physiological and Pathophysiological Insights of Nav1.4 and Nav1.5 Comparison.
Loussouarn G, Sternberg D, Nicole S, Marionneau C, Le Bouffant F, Toumaniantz G, Barc J, Malak OA, Fressart V, Péréon Y, Baró I,
Charpentier F.
Front Pharmacol. 2016 Jan 14 (2015);6:314.

Urine-sample-derived human induced pluripotent stem cells as a model to study PCSK9-mediated autosomal dominant hypercholesterolemia.
Si-Tayeb K*, Idriss S*, Champon B, Caillaud A, Pichelin M, Arnaud L, Lemarchand P, Le May C, Zibara K, Cariou B.
Dis Model Mech. 2016 Jan 1;9(1):81-90.

Maternal exposure to GOS/Inulin mixture prevents food allergies and promotes tolerance in offspring in mice.
Bouchaud G*, Castan L*, Chesné J, Braza F, Aubert P, Neunlist M, Magnan A, Bodinier M.
Allergy. 2016 Jan;71(1):68-76.

Targeted resequencing identifies TRPM4 as a major gene predisposing to progressive familial heart block type I.
Daumy* X, Amarouch* M-Y, Lindenbaum P, Bonnaud S, Charpentier E, Bianchi B, Nafzger S, Baron E, Fouchard S, Thollet A, Kyndt F, Barc J, Le Scouarnec S, Makita N, Le Marec H, Dina C, Gourraud J-B, Probst V, Abriel* H, Redon* R, Schott* J-J. 
Int J Cardiol. 2016;207:349-358.