Nabila Bouatia-Naji, University of Paris Cité

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  • Le 26 January 2024
    Amphi DE
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  • 11h30

Leveraging Genetics and Genomics to Understand and Model Understudied Arterial Diseases

Leveraging Genetics and Genomics to Understand and Model Understudied Arterial Diseases


Nabila Bouatia-Naji, PhD, DR1 Inserm, Chef d'équipe PARCC
PARCC Inserm, Université Paris Cité


Abstract

Nabila Bouatia-Naji current efforts are focused on the study of the genetics of atypical vascular diseases with high prevalence in women, mainly fibromusuclar dysplasia and spontaneous coronary artery dissection (SCAD). The multidisciplinary team that she leads is based at the Paris Cardiovascular Research Center, , Inserm U970 and includes statistical geneticists, molecular biologists and clinicians. They use cutting-edge genetic epidemiology and functional genomics methods applied in high through-put cell models. In the last decade, she established the genetic models for these diseases and identified their first genetic causes that she is currently following up and modelling using high throughput iPS derived vascular cells. She authored over 90 publications and is a recognized researcher in the genetics of women specific cardiovascular disease. She is an active advocate for more leadership opportunities for women in health sciences, and generally in STEM.
 

Biographie

Nabila Bouatia-Naji holds a PhD in Human Genetics delivered by Lille University in 2006. She is director of research and Team Leader at the Paris Cardiovascular Research Center (PARCC), Inserm and Université Paris Cité. She initially worked on the genetics of diabetes related metabolic traits, mainly fasting glucose. She moved her interest to cardiovascular disease, starting by seminal work on mitral valve prolapse on its genetic and molecular basis, as a member of a Leducq Network. Nabila Bouatia-Naji current efforts are focused on the study of the genetics of atypical vascular diseases with high prevalence in women, mainly for fibromusuclar Dysplasia and Spontaneous Coronary Artery Dissection (SCAD). Her multidisciplinary team includes statistical geneticists, molecular biologists and clinicians uses cutting-edge genetics and functional genomics methods applied in high through-put cell models. In the recent decade, she established the genetic models for these diseases and identified their first genetic causes that she is currently following up and modelling using high throughput iPS derived vascular cells.

She authored over 90 publications and is a recognized researcher in the genetics of women specific cardiovascular disease. She is an active advocate for more leadership opportunities for women in health sciences, and generally in STEM. Nabila Bouatia-Naji has received several awards from l’Academie des Sciences in France, the International Conference of Human Genetics, Japan, the African Acadamy of Sciences, the European Research Council. She was this year Award for Cardiovascular investigation through the Jean-Paul Binet FRM.

Mis à jour le 18 January 2024.
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