Thomas MOORE-MORRIS, Marseille Medical Genetics
  • Le 03 mai 2019
    Institut de Recherche en Santé - 8 quai Moncousu - Nantes
    Amphithéâtre Denis Escande
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  • 11h30

Cardiac lineage specification in development and disease

Cardiac lineage specification in development and disease

Thomas MOORE-MORRIS, PhD, invited by Jean Mérot (Eq I)

CRCN, Marseille Medical Genetics / UMR1251


During my first postdoc with Sylvia Evans (UCSD), I studied the origins of cardiac fibroblasts during development and in heart failure notably using genetic lineage tracing in mice. Following this, I joined Michel Puceat's group in Marseille where I focused on more epigenetic aspects of cardiac lineage specification, using approaches such as cardiac differentiation of stem cells and single cell RNA-seq (scRNA-seq) to understand the role of NIPBL (required for chromatin structure regulation) in cardiogenesis. My current and future projects involve studying the epigenome of cardiac fibroblasts and their role in cardiac regeneration.
Mis à jour le 15 avril 2019.