• Le 07 February 2020
    Institut de Recherche en Santé - 8 quai Moncousu - Nantes
    Amphithéâtre Denis Escande
  • 11h30

De l'(épi)génomique à la médecine de précision des diabètes et obésités

De l'(épi)génomique à la médecine de précision des diabètes et obésités

Pr. Philippe Froguel invited by Samy Hadjadj (Eq IV)
Head of UMR CNRS 8199-Université de Lille, Labex EGID, Equipex LIGAN-Médecine Personnalisée and Centre National de Médecine de Précision PreciDIAB

Abstract

4P medicine (predictive, preventive, personalized and participatory) is on the way in metabolic diseases including diabetes and obesity. This is the task of the new National Center of PreciDIAB Precision Medicine which has just been created. The scientific reasons for advancing in this direction and the means to do so will be discussed.


Biography

Philippe Froguel passed his Medical Degree in 1986 and he obtained a PhD in 1991 from Paris University. He is currently Professor of Genomic Medicine and head of the section of genomics of common disease in the department of medicine at the Hammersmith hospital, Imperial College London, UK. He is also Professor of Endocrinology at Lille University hospital, France, director of the CNRS/Lille University/Pasteur Institute research group "Integrated Genomics and Modelling of Metabolic Diseases", Director of the French laboratory of excellence on diabetes research EGID and of the equipment of excellence in genomics LIGAN-Personalized Medicine. In 2019 he will head the new French National Centre for Precision Medicine in diabetes PreciDIAB.  PF's scientific career focuses on the genetics of diabetes and obesity. He is author of >680 Pubmed indexed publications and his H-index is 154. He is among the most cited researchers in medical research (>100,000). Philippe Froguel has identified in 1992 the first diabetes gene (glucokinase), in 1998 the most prevalent cause of monogenic obesity (MC4R, in 2007 the first gene for common obesity (FTO) and has published in 2007 the first Genome Wide Association Study in T2D.