Isabelle Baró, Nathalie Gaborit

In this program, we aim to identify the pathophysiological mechanisms of inherited cardiac arrhythmias by combining molecular, cyto/histological and electrophysiological studies on cardiomyocytes generated from induced pluripotent stem cells obtained from affected patients and on knock-in mouse models.

Our projects are mostly focused on the Brugada syndrome and familial catecholamine-induced QT prolongation.