FFC IMPULSION - Solena LE SCOUARNEC (2025)
Background: Mitral valve prolapse (MVP) is a common heart disease affecting 2-3% of the population. The condition results from problems with the heart's mitral valve, causing malfunctions in the bloodstream. Recent research has identified several genes linked to MVP, paving the way for a better understanding of its biological mechanisms.
Objectives: The aim of the project is to study the impact of mutations in a new gene on MVP. Genetically modified mouse models will be used to observe the effects of these mutations. The researchers will use advanced techniques to confirm the relevance of these models by imaging.
Expected results in terms of public health: The expected results include a better understanding of the genetic causes of MVP and the development of new models for studying this pathology. In the long term, this could lead to the identification of new therapeutic targets and more effective treatments, thereby improving the management of patients suffering from MVP.
Objectives: The aim of the project is to study the impact of mutations in a new gene on MVP. Genetically modified mouse models will be used to observe the effects of these mutations. The researchers will use advanced techniques to confirm the relevance of these models by imaging.
Expected results in terms of public health: The expected results include a better understanding of the genetic causes of MVP and the development of new models for studying this pathology. In the long term, this could lead to the identification of new therapeutic targets and more effective treatments, thereby improving the management of patients suffering from MVP.
Mis à jour le 05 February 2025.