Bertrand CARIOU  MD, PhD, Professor of Endocrinology, CHU Nantes

B. Cariou obtained his MD (University of Nantes) and PhD (University Paris XI) in 2003.
He completed his post-doctoral training at the Institut Pasteur, Lille (Pr B. Staels) on the metabolic role of the bile acid receptor FXR.
He joined l’institut du thorax in 2006 and became Professor of Endocrinology at the Nantes University Hospital in 2009. Since 2015, he has been the elected director of l’institut du thorax.
He obtained the Apollinaire Bouchardat (2009) and Auguste Loubatières (2017) awards from the French Society of Diabetes.
Pr. Cariou is interested in the function of PCSK9 and is a core member of a TransAtlantic Network of Excellence on PCSK9 funded by the Fondation Leducq (2014–2019).
He is also the coordinator of RHU project CHOPIN (2016-2021), aiming to identify new targets in LDL-cholesterol metabolism.

David JACOBI  MD, PhD, Professor of Nutrition, CHU Nantes

D. Jacobi is specialized in the metabolic complications of overnutrition.
After doctoral studies on physical activity assessment in daily life and its applications in subjects with low physical activity levels (PhD, 2011, University of Tours, FR), he moved to the Harvard School of Public Health in Boston for a postdoctoral fellowship. He studied the circadian regulation of liver metabolism in the Department of genetics and complex diseases (Pr. Chih-Hao Lee).
His research area is on the molecular mechanisms of metabolic diseases in the context of obesity with a focus on the alteration of daily metabolic cycles of sub-cellular organelles.
David Jacobi is a laureate of an “ATIP-Avenir 2016 grant”: a joint CNRS/ Inserm French grant aiming at attracting young high-level researchers to lead research teams on new research topics.
He joined l’institut du thorax to develop a new research team.